Health Briefs

health brief

Serotonin Theory of Depression Debunked

Serotonin Theory of Depression Debunked - freshidea/

The idea that depression is caused by a chemical imbalance—specifically, a serotonin deficiency—has been popular and influential since the 1960s, leading to the wide use of antidepressants. A recent multi-institution study led by the University of Reading, in the UK, and published in Molecular Psychiatry has debunked this theory.

The researchers did a systematic review of studies on the topic and found no convincing evidence of an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations.

The serotonin theory of depression has historically provided convincing justification for the use of antidepressants and may discourage people from discontinuing treatment, potentially leading to lifelong dependence on such drugs. 

Read 451 times


We do not necessarily endorse the views expressed in the articles and advertisements contained on this website, nor are we responsible for the products and services advertised.

The information contained herein is not intended to diagnose, treat, cure or prevent any disease or medical condition. Always seek the advice of your medical professional.

Recent Featured Articles

  • Loving Our Kidneys   Edible Allies, Integrative Treatments and Lifestyle Tips   Our kidneys are prodigious multitaskers.…
  • Veggies for the Win   Five Reasons to Choose a Plant-Based Lifestyle   Many of us have…

Contact Information

Michigan Healthy Living
& Sustainability, Inc.
d.b.a. Natural Awakenings of East Michigan
PO Box 283, Oxford, MI 48371

Telephone: 248-628-0125
Contact us by eMail